2019

Predicting Postoperative Liver Dysfunction Based on Blood Derived MicroRNA Signatures. Starlinger P, Hackl H, Pereyra D, Skalicky S, Geiger E, Finsterbusch M, Tamandl D, Brostjan C, Grünberger T, Hackl M, Assinger A.

Hepatology 2019

Intrahepatic fibrin(ogen) deposition drives liver regeneration after partial hepatectomy in mice and humans. Groeneveld D, Pereyra D, Veldhuis Z, Adelmeijer J, Ottens P, Kopec AK, Starlinger P, Lisman T, Luyendyk JP. (equally contributing last author)

Blood. 2019

Mutational profile of colorectal cancer lung metastases and paired primary tumors by targeted next generation sequencing: implications on clinical outcome after surgery.

Schweiger T, Liebmann-Reindl S, Glueck O, Starlinger P, Laengle J, Birner P, Klepetko W, Pils D, Streubel B, Hoetzenecker K. 

J Thorac Dis. 2018

The Combination of APRI and ALBI Facilitates Preoperative Risk Stratification for Patients Undergoing Liver Surgery After Neoadjuvant Chemotherapy.Pereyra D, Rumpf B, Ammann M, Perrodin SF, Tamandl D, Haselmann C, Stift J, Brostjan C, Laengle F, Beldi G, Gruenberger T, Starlinger P.

Ann Surg Oncol. 2019

2018

Elevated ADAMTS13 Activity is Associated with Poor Postoperative Outcome in Patients Undergoing Liver Resection. Haegele S, Fuxsteiner J, Pereyra D, Koeditz C, Rumpf B, Schuetz C, Schwarz C, Brostjan C, Gruenberger T, Starlinger P.

Sci Rep. 2018

Neutrophil-Mediated Proteolysis of Thrombospondin-1 Promotes Platelet Adhesion and String Formation. Seif K, Alidzanovic L, Tischler B, Ibrahim N, Zagrapan B, Rauscher S, Salzmann M, Hell L, Mauracher LM, Budde U, Schmid JA, Jilma B, Pabinger I, Assinger A, Starlinger P, Brostjan C.

Thromb Haemost. 2018

Responding to the challenges of international collaborations between the east and the west – report of the first JCOG-EORTC symposium and a perspective from young JCOG and EORTC investigators. Kataoka K, Kaider-Person O, Kasper B, Starlinger P, Caballero C, Menis J, Hendriks LE, Terada M, Collette L, Nakamura K, Lacombe D, Fukuda H.

Jpn J Clin Oncol. 2019 Jan

Mesh-augmented versus direct abdominal closure in patients undergoing open abdomen treatment. Jakob MO, Schwarz C, Haltmeier T, Zindel J, Pinworasarn T, Candinas D, Starlinger P, Beldi G.

Hernia. 2018

DNA damage predicts prognosis and treatment response in colorectal liver metastases superior to immunogenic cell death and T cells.Laengle J, Stift J, Bilecz A, Wolf B, Beer A, Hegedus B, Stremitzer S, Starlinger P, Tamandl D, Pils D, Bergmann M.

Theranostics. 2018

Shaping the future of liver surgery: Implementation of experimental insights into liver regeneration. Pereyra D, Starlinger P.

Eur Surg. 2018

Reply to: “Intra-platelet serotonin in prognosis of tumorigenesis: Friend or foe?”

Pereyra D, Starlinger P.

J Hepatol. 2018

Reply.

Pereyra D, Starlinger P.

Hepatology. 2018

Optimized plasma preparation is essential to monitor platelet-stored molecules in humans. Mussbacher M, Schrottmaier WC, Salzmann M, Brostjan C, Schmid JA, Starlinger P, Assinger A.

PLoS One. 2017

Microscopic biliary and perineural invasion and clinical outcome after neoadjuvant bevacizumab-based chemotherapy and liver resection in patients with colorectal liver metastases. Stift J, Graf A, Schwarz C, Tamandl D, Starlinger P, Herac M, Beer A, Wrba F, Bodingbauer M, Kaczirek K, Stremitzer S.

Eur J Surg Oncol. 2018

Von Willebrand Factor Dynamics are Associated with Liver Regeneration and Predict Outcome after Liver Resection. Starlinger P, Pereyra D,  Haegele S, Braeuer P, Oehlberger L, Primavesi F, Kohler A, Offensperger F, Reiberger T, Ferlitsch A, Messner B, Beldi G, Staettner S, Brostjan C, Gruenberger T.

Hepatology 2018

2017

Bivalent role of Intra-Platelet Serotonin in Liver Regeneration and Tumor Recurrence in Humans. Padickakudy R, Pereyra D, Offensperger F, Jonas P, Oehlberger L, Schwarz C, Haegele S, Assinger A, Brostjan C, Gruenberger T, Starlinger P.

J Hepatol. 2017

Soluble Axl is an accurate biomarker of cirrhosis and hepatocellular carcinoma development: results from a large scale multicenter analysis. Dengler M, Staufer K, Huber H, Stauber R, Bantel H, Weiss KH, Starlinger P, Pock H, Klöters-Plachky P, Gotthardt DN, Rauch P, Lackner C, Stift J, Brostjan C, Gruenberger T, Kumada T, Toyoda H, Tada T, Weiss TS, Trauner M, Mikulits W.

Oncotarget. 2017

Early prediction of postoperative liver dysfunction and clinical outcome using antithrombin III-activity. Pereyra D, Offensperger F, Klinglmueller F, Haegele S, Oehlberger L, Gruenberger T, Brostjan C, Starlinger P.

PLoS One. 2017

2016

The FXR agonist PX20606 ameliorates portal hypertension by targeting vascular remodelling and sinusoidal dysfunction. Schwabl P,Hambruch E,Seeland BA,Hayden H,Wagner M, Garnys L,Strobel B,Schubert TL,Riedl F,Mittereger D,Burnet M,Starlinger P,Oberhuber G,Deuschle U,Rohr-Udilova N, Podesser BK,Peck-Radosavljevic M, Reiberger T,Kremoser C,Trauner M.

J Hepatol. 2016

Perioperative Non-Invasive Indocyanine Green-Clearance Testing to Predict Postoperative Outcome after Liver Resection. Haegele S, Reiter S, Wanek D, Offensperger F, Pereyra D, Stremitzer S, Fleischmann E, Brostjan C, Gruenberger T, Starlinger P. .

PLoS One. 2016

The VEGF rise in blood of bevacizumab patients is not based on tumor escape but a host-blockade of VEGF clearance. Alidzanovic L, Starlinger P, Schauer D, Maier T, Feldman A, Buchberger E, Stift J, Koeck U, Pop L, Gruenberger B, Gruenberger T, Brostjan C. .

Oncotarget. 2016

Chemotherapy of colorectal liver metastases induces a rapid rise in intermediate blood monocytes which predicts treatment response. Schauer D, Starlinger P, Alidzanovic L, Zajc P, Maier T, Feldman A, Padickakudy R, Buchberger E, Elleder V, Spittler A, Stift J, Pop L, Gruenberger B, Gruenberger T, Brostjan C. 

Oncoimmunology. 2016

Importance of platelet-derived growth factors in liver regeneration. Starlinger P, Assinger A.

Expert Rev Gastroenterol Hepatol. 2016

P2X1 regulated IL-22 secretion by innate lymphoid cells is required for efficient liver regeneration.Kudira R, Malinka T, Kohler A, Dosch M, Gomez de Agüero M, Melin N, Haegele S, Starlinger P, Maharjan N, Saxena S, Keogh A, Stroka D, Candinas D, Beldi G.

Hepatology. 2016

Defective intra-platelet vascular endothelial growth factor release is associated with liver dysfunction following partial hepatectomy. Starlinger P, Assinger A.

Hepatology. 2016

2015

The Profile of Platelet alpha-Granule Released Molecules Affects Postoperative Liver Regeneration. P. Starlinger, S. Haegele, F. Offensperger, L. Oehlberger, D. Pereyra, J. B. Kral, W. C. Schrottmaier, S. Badrnya, T. Reiberger, A. Ferlitsch, J. Stift, F. Luf, C. Brostjan, T. Gruenberger, and A. Assinger. 

Hepatology 2015

Histological response, pattern of tumor destruction and clinical outcome after neoadjuvant chemotherapy including bevacizumab or cetuximab in patients undergoing liver resection for colorectal liver metastases. Stremitzer, S., J. Stift, J. Singh, P. Starlinger, B. Gruenberger, D. Tamandl, and T. Gruenberger. 

European journal of surgical oncology 2015

CEA Change After Neoadjuvant Chemotherapy Including Bevacizumab and Clinical Outcome in Patients Undergoing Liver Resection for Colorectal Liver Metastases. Stremitzer, S., J. Stift, A. Graf, J. Singh, P. Starlinger, B. Gruenberger, D. Tamandl, and T. Gruenberger. 2015.

Annals of surgical oncology 2015

Plasma thrombospondin 1 as a predictor of postoperative liver dysfunction. Starlinger, P., S. Haegele, D. Wanek, S. Zikeli, D. Schauer, L. Alidzanovic, E. Fleischmann, B. Gruenberger, T. Gruenberger, and C. Brostjan.

The British journal of surgery 2015

Stromal expression of heat-shock protein 27 is associated with worse clinical outcome in patients with colorectal cancer lung metastases. Schweiger, T., C. Nikolowsky, P. Starlinger, D. Traxler, M. Zimmermann, P. Birner, B. Hegedus, B. Dome, M. Bergmann, M. Mildner, W. Klepetko, K. Hoetzenecker, and H. J. Ankersmit.

 PloS one 2015

Assessing the TP53 marker type in patients treated with or without neoadjuvant chemotherapy for resectable colorectal liver metastases: A p53 Research Group study. Pilat, N., T. Grunberger, F. Langle, M. Mittlbock, B. Perisanidis, S. Kappel, B. Wolf, P. Starlinger, I. Kuhrer, F. Muhlbacher, and D. Kandioler. 

European journal of surgical oncology 2015

 Plasma fibrinogen and blood platelet counts are associated with response to neoadjuvant therapy in esophageal cancer.Ilhan-Mutlu, A., P. Starlinger, T. Perkmann, S. F. Schoppmann, M. Preusser, and P. Birner. 

Biomarkers in medicine 2015

eficiency in Thrombopoietin Induction after Liver Surgery Is Associated with Postoperative Liver Dysfunction. Haegele, S., F. Offensperger, D. Pereyra, E. Lahner, A. Assinger, E. Fleischmann, B. Gruenberger, T. Gruenberger, C. Brostjan, and P. Starlinger. 

PloS one 2015

2014

Reply. Starlinger, P., M. Lesurtel, C. Brostjan, P. A. Clavien, and T. Gruenberger.

Hepatology 2014

Role of platelets in systemic tissue protection after remote ischemic preconditioning. Starlinger, P., and T. Gruenberger.

Hepatology 2014

Starlinger, P., C. Brostjan, and T. Gruenberger. 2014. Evidence for serotonin as an inducer of liver regeneration in humans – further investigations. 

Hepatology 2014

 Evidence for serotonin as a relevant inducer of liver regeneration after liver resection in humans. Starlinger, P., A. Assinger, S. Haegele, D. Wanek, S. Zikeli, D. Schauer, P. Birner, E. Fleischmann, B. Gruenberger, C. Brostjan, and T. Gruenberger.

Hepatology 2014

Monocytes with angiogenic potential are selectively induced by liver resection and accumulate near the site of liver regeneration. Schauer, D., P. Starlinger, P. Zajc, L. Alidzanovic, T. Maier, E. Buchberger, L. Pop, B. Gruenberger, T. Gruenberger, and C. Brostjan. 

BMC immunology 2014

Multicenter analysis of soluble Axl reveals diagnostic value for very early stage hepatocellular carcinoma. Reichl, P., M. Fang, P. Starlinger, K. Staufer, R. Nenutil, P. Muller, K. Greplova, D. Valik, S. Dooley, C. Brostjan, T. Gruenberger, J. Shen, K. Man, M. Trauner, J. Yu, C. F. Gao, and W. Mikulits.

International journal of cancer 2014

2013

Clinical evidence for thrombospondin-1 as a relevant suppressor of liver regeneration. Starlinger, P., D. Schauer, L. Alidzanovic, S. Zikeli, K. Gebhardt, F. Luf, E. Fleischmann, B. Perisanidis, B. Gruenberger, T. Gruenberger, and C. Brostjan.

Journal of hepatology 2013

Postoperative failure of platelet recovery is an independent risk factor for poor survival in patients with oral and oropharyngeal cancer. Perisanidis, C., M. Mittlbock, A. Schoppmann, G. Kornek, P. Starlinger, A. Stift, E. Selzer, C. Schopper, and R. Ewers. 

Clinical oral investigations 2013

2012

Neoadjuvant bevacizumab persistently inactivates VEGF at the time of surgery despite preoperative cessation. Starlinger, P., L. Alidzanovic, D. Schauer, T. Maier, C. Nemeth, B. Perisanidis, D. Tamandl, B. Gruenberger, T. Gruenberger, and C. Brostjan.

British journal of cancer 2012

Intermediate monocytes but not TIE2-expressing monocytes are a sensitive diagnostic indicator for colorectal cancer. Schauer, D., P. Starlinger, C. Reiter, N. Jahn, P. Zajc, E. Buchberger, T. Bachleitner-Hofmann, M. Bergmann, A. Stift, T. Gruenberger, and C. Brostjan.

PloS one 2012

Secretome of apoptotic peripheral blood cells (APOSEC) attenuates microvascular obstruction in a porcine closed chest reperfused acute myocardial infarction model: role of platelet aggregation and vasodilation. Hoetzenecker, K., A. Assinger, M. Lichtenauer, M. Mildner, T. Schweiger, P. Starlinger, A. Jakab, E. Berenyi, N. Pavo, M. Zimmermann, C. Gabriel, C. Plass, M. Gyongyosi, I. Volf, and H. J. Ankersmit.

Basic research in cardiology 2012

Myelosuppression of thrombocytes and monocytes is associated with a lack of synergy between chemotherapy and anti-VEGF treatment. Starlinger, P., P. Brugger, D. Schauer, S. Sommerfeldt, D. Tamandl, I. Kuehrer, S. F. Schoppmann, M. Gnant, and C. Brostjan.

Neoplasia 2012

2011

Discrimination between circulating endothelial cells and blood cell populations with overlapping phenotype reveals distinct regulation and predictive potential in cancer therapy. Starlinger, P., P. Brugger, C. Reiter, D. Schauer, S. Sommerfeldt, D. Tamandl, I. Kuehrer, S. F. Schoppmann, M. Gnant, and C. Brostjan.

Neoplasia 2011

Platelet-stored angiogenesis factors: clinical monitoring is prone to artifacts. Starlinger, P., L. Alidzanovic, D. Schauer, P. Brugger, S. Sommerfeldt, I. Kuehrer, S. F. Schoppmann, M. Gnant, and C. Brostjan. 

Dis Markers 2011

2010

S.ystemic effects of anti-VEGF therapy – Mini-reviewStarlinger P., G. K., Gruenberger T. , Brostjan C.

European Surgery 2010

Thrombospondin-1: a unique marker to identify in vitro platelet activation when monitoring in vivo processes. Starlinger, P., H. P. Moll, A. Assinger, C. Nemeth, K. Hoetzenecker, B. Gruenberger, T. Gruenberger, I. Kuehrer, S. F. Schoppmann, M. Gnant, and C. Brostjan. 

Journal of thrombosis and haemostasis 2010